Database category coverage

Every entry in the Current Agreements deals and alliances database is categorized
to the fullest extent possible using the following fields:

• Date
• Parties to deal
• Financials
• Industry sector
• Therapy areas
• Technology type
• Deal components
• Stage of development
• Exclusivity
• Asset type
• Geographic focus
• Excluded geography

The following provides a more detailed description of each field used when
categorizing the scope of each database deal entry.

Industry sector

Every deal is categorized according to the industry focus of each of the parties to
the deal using the following categories:

• Bigpharma
• Pharmaceuticals
• Biotech
• Diagnostics
• Drug delivery
• Medical devices
• Consumer health
• Specialty pharma
• Generic pharma
• Agricultural
• Animal health
• Academic
• Non-profit
• Government
• Financial
• Research tools
• Service companies
  
  

Therapy areas

Where relevant, every deal entry is categorized by the therapy focus of the alliance
activity, down to the individual disease. The following top level therapy areas are
covered, each being divided into numerous subcategories:

• Anesthesia
• Cardiovascular
• Central nervous system
• Cosmetic products
• Dental
• Dermatology
• Gastrointestinal
• Genetic disorders
• Genitourinary
• Gynecology
• Hematology
• Hospital care
• Immunology
• Infectives
• Inflammatory
• Metabolic
• Musculoskeletal
• Obstretics
• Oncology
• Ophthalmology
• Psychiatry
• Public health
• Respiratory
• Sensory organs
• Sexual health
  
  

Technology type

Each database deal entry is categorized by the type of technology included in the deal
between the parties, where relevant.

Just some of the technology types included:

• Antibiotics
• Antibodies
• Bioinformatics
• Biologicals
• Biomarkers
• Biomaterials
• Biosimilars
• Cell culture
• Cell therapy
• Companion diagnostics
• Compound library
• Devices
• Diagnostics
• Discovery tools
• DNA probes
• Drug delivery
• Epigenetics
• Gene therapy
• Genomics
• Glycomics
• High throughput screening
• Imaging
• Implant
• In vitro diagnostics
• Microarray
• Molecular diagnostics
• Nanotechnology
• Organ regeneration
• Peptides
• Personalized medicine
• Pharmacogenomics
• Proteomics
• Recombinant DNS
• Regenerative medicine
• RNA therapeutics
• Stem cells
• Tissue regeneration
• Transgenics
• Vaccines

Plus many more.

Most technology categories are further subdivided into specific technology sub categories.

Deal components

Indepth analysis of every deal ensures comprehensive categorization according to the
components of the deal. The following categories are included:

• Asset purchase
• Assignment
• Co-development
• Co-market
• Co-promotion
• Collaborative R&D
• Contract service
• CRADA
• Cross-licensing
• Development
• Distribution
• Equity purchase
• Evaluation
• Grant
• Joint venture
• Licensing
• Litigation
• Loan
• Manufacturing
• Marketing
• Option
• Promotion
• Research
• Royalty financing
• Settlement
• Spin out
• Sub license
• Supply
• Termination
• Warrant

M&A activity is tracked in a separate dedicated database within the
Current Agreements subscription.

Stage of development

Every deal entry is categorized according to stage of development at
the time of signing, where relevant and available. The following categories
are used:

• Discovery
• Preclinical
• Phase I
• Phase II
• Phase III
• Regulatory
• Marketed
• Formulation
  
  

Geographic focus

The geographic focus of each deal entry is captured, where available to
enable users to filter search results to specific geographic location.

Geographic focus is assigned using the following hierarchy:

• Worldwide
• Continent
• Country
  
  

Excluded geography

Excluded geography is used where a deal entry explicitly states that one
of more territories are excluded from the deal.

Excluded geography is assigned using the following hierarchy:

• Worldwide
• Continent
• Country
  
  

Additional categories

• Exclusivity
• Asset type

Online sources

The following online sources have been used to provide content for the
Current Agreements deals and alliances database.

Press releases

Individual press releases as found on company websites or other distributors
of press release announcements as made publically available from time to time.

Company SEC filings

10K, 10Q, 20F, 8K, S1's...we capture them all and more, providing details
not found in press releases, inccluding additional financials.

Contract documents

Contract documents provided in the database are sourced from the SEC website
found at www.sec.gov.

Company presentations

Company presentations within the database are sourced from the SEC website
found at www.sec.gov as well as conferences worldwide.

Additional deal information

Any additional deal information has been obtained from publicly available
sources including company websites, SEC filings, conference presentations or
personal discussion between company representatives and our experts.
Where relevant, sources have been identified to allow data verification.

Exchange rates

All financial values in this database have been expressed in US$.
Where an amount was originally reported in a currency other than US$, the
online currency exchange www.xe.com was used to obtain an exchange rate
between the relevant currency and US$ on the date of the deal announcement.
The US$ amount then determined, was entered into the database.

Database definitions

All terms used in the Current Agreements database are explained in the
Definitions section, available to subscribers from each database entry page.